• Physician Profile

    Geoffrey R. Oxnard, MD

     
    Geoffrey R. Oxnard, MD

     
    Instructor in Medicine, Harvard Medical School

    Center/Program

    Thoracic Oncology

    Office phone: 617-632-6049
    Appointment phone: 617-632-5304
    Fax: 617-632-5786

    Preferred contact method: office phone
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    Discipline

    Medical Oncologist

    Research Department

    Medical Oncology

    Interests

    Acquired resistance to erlotinib, Genotype-defined subsets of lung cancer, Familial lung cancer syndromes


    Dana-Farber Cancer Institute
    450 Brookline Avenue
    Boston, MA 02215

    Biography

    I am a thoracic oncologist with two primary areas of research. Through collaborations with molecular pathologists and laboratory researchers, I am interested in identifying subpopulations of lung cancer with unique clinical and molecular characteristics. For example, we have recently identified that lung cancer patients with T790M-mediated acquired resistance to erlotinib (Tarceva) have a favorable outcome, likely indicating a need for a unique therapeutic strategy.

    Additionally, I perform research with colleagues in radiology and medical physics to explore better ways of analyzing response and progression in clinical trials and correlative research. In a recent analysis, we showed that volumetric CT measurement after only 3 weeks of gefitinib is able to accurately distinguish which lung cancers harbor sensitizing mutations. Multiple analyses of industry and cooperative group imaging data are ongoing through collaborations with Lawrence Schwartz, Chair of Radiology, Columbia University. 

    Background

    Board Certification
    Internal Medicine, 2008
    Medical Oncology, 2010

    Fellowship
    Memorial Sloan-Kettering Cancer Center, Medical Oncology, 2011

    Residency
    Massachusetts General Hospital, Internal Medicine, 2008

    Medical School
    University of Chicago Pritzker School of Medicine, 2005

    Recent Awards

    • Young Investigator Award, ASCO Cancer Foundation, 2010; Merit Award, ASCO Annual Meeting, 2010, 2010