• Physician Profile

    Osama Rahma, MD

    Osama Rahma, MD
    Medical Oncologist, Center for Immuno-Oncology
    Medical Oncologist, Gastrointestinal Oncology

    Assistant Professor of Medicine, Harvard Medical School


    Gastrointestinal Cancer
    Center for Immuno-Oncology

    Office phone: 617-632-2563
    Appointment phone: 617-632-2070
    Fax: 617-582-7227

    Preferred contact method: office phone
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    Medical Oncology


    Immunotherapy, Gastrointestinal cancers, Pancreatic cancer

    Dana-Farber Cancer Institute
    450 Brookline Avenue
    Boston, MA 02215


    Dr. Rahma received his medical degree from University of Damascus in 1998. He completed his residency in Internal Medicine at East Carolina University followed by Geriatrics Fellowship at University of Hawaii. Dr. Rahma joined the National Cancer Institute (NCI) as an Immunotherapy Research Fellow in the Vaccine Branch in 2009 and completed a Fellowship in Medical Oncology in 2013 specializing in Cancer Immunotherapy and Gastrointestinal (GI) Oncology. While at NCI, his efforts led to the development of many clinical studies investigating immunotherapy in GI malignancies. 

    Prior to joining Dana-Farber Cancer Institute, Dr. Rahma was the co-leader of the Hepatobiliary and Pancreatic Cancer Program at University of Virginia where he led translational research efforts as the Principal Investigator of many clinical trials. Dr. Rahma joined the Center for Immuno-Oncology at Dana-Farber to be part of national and international efforts to advance the field of Cancer Immunotherapy. He is currently the chair of two investigator-initiated clinical trials using a novel combination of immune checkpoint inhibitor (anti-PD-1) and neoadjuvant chemoradiation in pancreatic and rectal cancer. During this exciting era of cancer immunotherapy and in collaboration with other investigators, Dr. Rahma will be investigating the combinations of variety of novel immunotherapeutic agents in multiple tumor types and working on identifying biomarkers that could determine clinical response.


    Board Certification
    Medical Oncology, 2013
    Internal Medicine, 2004

    National Cancer Institute, National Institutes of Health, Hematology/Medical Oncology

    East Carolina University, Internal Medicine

    Medical School
    Damascus University

    Recent Awards

    • Danny Danielson Translational Innovation Award, Hoosier Cancer Research Network, 2015
    • Oncology Trainee Award, The Conquer Cancer Foundation of ASCO, 2012
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