• Researcher Profile

    Ursula A. Matulonis, MD

    Ursula A. Matulonis, MD

    Top Doctor

    Director, Gynecologic Oncology
    Institute Physician

    Professor of Medicine, Harvard Medical School


    Gynecologic Oncology

    Office phone: 617-632-2334
    Fax: 617-632-3479

    Preferred contact method: office phone

    View Physician Profile

    Research Department

    Medical Oncology/Solid Tumor Oncology


    Gynecologic malignancies, New therapies for gynecologic cancers

    Area of Research

    Clinical Trials in Gynecologic Malignancies

    Dana-Farber Cancer Institute
    450 Brookline Avenue
    Boston, MA 02215


    Ursula A. Matulonis, MD is Medical Director and Program Leader of the Medical Gynecologic Oncology Program at Dana-Farber Cancer Institute and Professor of Medicine at Harvard Medical School. Her research focuses on targeted therapies for gynecologic malignancies, with a specific interest in the genetic changes in ovarian cancer and how that can lead to rationale targeted drug selection. Dr. Matulonis is the Principal Investigator of several clinical trials and translational studies for ovarian cancer. Dr. Matulonis is a Co-PI on an ovarian cancer SPORE project entitled “Identification of Oncogenic Mutations in Ovarian Cancer,” and a Co-PI on the project “Genetic relationships between breast and ovarian cancer” that is funded by the Breast Cancer Research Foundation. She is also a past recipient of a DF/HCC Ovarian Cancer SPORE Developmental Grant entitled “Genetic Fingerprinting of Ovarian Cancer.” 

    Dr. Matulonis serves on the National Comprehensive Cancer Network Ovarian Cancer Recommendation and Guideline Committee for both ovarian cancer and for the treatment of anemia, the Gynecologic Oncology Group Quality of Life Committee, a member of The Cancer Genome Atlas Project (TCGA) Endometrial Analysis Working Group, and is Medical Director and Board Member for the non-profit organization Ovations for the Cure. She is a recipient of the Dennis Thompson Compassionate Care Scholar award, the Lee Nadler “Extra Mile” Award, and was named one of Boston’s Best Physicians in Medical Oncology by Boston Magazine numerous times. She serves on the editorial board of the Journal of Clinical Oncology.

    After receiving her MD from Albany Medical College, she completed an internship and residency at the University of Pittsburgh, followed by a medical oncology fellowship at Dana-Farber.

    Recent Awards

    • Partners in Excellence Award, Partners Health Care, 2010
    • "Boston Magazine" Best Doctors, 2009
    • Lee Nadler "Extra Mile" Award, 2009
    • Dennis Thompson Compassionate Care Scholar, Brigham and Women's Hospital, 2000
    • Partners in Excellence Award, Partners Health Care, 2000


    Clinical Trials in Gynecologic Malignancies

    The Medical Gynecologic Oncology Program serves as the infrastructure for clinical and translational research at Dana-Farber Cancer Institute.

    Our research involves testing novel drugs and biologics in newly diagnosed as well as recurrent gynecologic tumors: ovarian, endometrial, cervical, vaginal, and vulvar cancers. A list of ongoing clinical trials is available via our website.

    Our integrated team of medical oncologists, gynecologic oncology surgeons, radiation oncologists, gynecologic oncology pathologists, clinical research team, and basic science researchers is immersed in a number of translational projects.

    Examples of ongoing projects in 2010 include the expression profiling and genotyping of ovarian cancer, the study of circulating tumor cells in ovarian cancer, investigation of HER3 expression and signalling and therapeutic potential of HER3, and the study of the PI3 kinase pathway in endometrial cancer.


    • Liu, Joyce, MD
View Researcher Directory
View Nurse Directory

Find a Clinical Trial

Support Cancer

Give Now