• Researcher Profile

    Hadine Joffe, MD, MSc

    Hadine Joffe, MD, MSc

    Top Doctor

    Director, Psycho-Oncology Research

    Associate Professor of Psychiatry, Harvard Medical School


    Psychosocial Oncology (Adult)

    Office phone: 617-732-4906
    Fax: 617-264-6326

    Preferred contact method: appointment phone

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    Women's mental health, Insomnia, Depression

    Dana-Farber Cancer Institute
    450 Brookline Avenue
    Boston, MA 02215


    Dr. Joffe received her undergraduate degree from Harvard University, her medical degree from Cornell University Medical College, and her Masters Degree in Epidemiology from the Harvard School of Public Health. She completed her psychiatry residency training at McLean Hospital and a fellowship in Reproductive Psychiatry at Massachusetts General Hospital.

    Dr. Joffe is an experienced clinician and researcher in women’s mental health. Her work focuses on the neural and endocrine mechanisms and treatment of menopausal symptoms of hot flashes, sleep disturbance, and depression in healthy women and cancer patients on anti-estrogen therapies. She is an R01-funded investigator who is studying the causes of sleep disturbance and depression during the menopause transition, particularly the role of estradiol and the contribution of hot flashes, as well as the best approaches to treating these menopause-related symptoms. In related women’s mental health research, she has investigated the effects on endogenous and exogenous reproductive hormones on mood and reproductive consequences of psychotropic medications.  

    In clinical work, Dr. Joffe takes care of women with vasomotor, sleep, mood and anxiety difficulties that occur during the menopause transition and in response to anti-estrogen therapies used to treat cancer, particularly in breast and GYN cancer patients.

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